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Ulcerative Colitis Panel

The Ulcerative Colitis Test combines antibody and related markers used in the evaluation of inflammatory bowel disease. It can support the assessment of ulcerative colitis when symptoms such as chronic diarrhea or abdominal discomfort are present.

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Typical turnaround
1-3 business days
Starting price
From $298
Results
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Quick answer

The Ulcerative Colitis Test groups laboratory markers that clinicians use when evaluating inflammatory bowel disease. It typically includes antibody tests such as pANCA and ASCA, along with inflammatory markers that reflect intestinal activity. The results support a broader assessment and are interpreted by a qualified healthcare provider alongside symptoms, imaging, and endoscopy.

What this test measures

Ulcerative colitis is a chronic inflammatory condition that affects the inner lining of the colon and rectum. It often causes persistent diarrhea, urgency, abdominal cramping, and blood in the stool. Because these symptoms overlap with other digestive conditions, clinicians use a combination of history, examination, imaging, and laboratory testing during evaluation.

The blood work in this order may include perinuclear antineutrophil cytoplasmic antibodies (pANCA), anti-Saccharomyces cerevisiae antibodies (ASCA), and general markers of inflammation such as C-reactive protein and a complete blood count. These tests do not replace endoscopy, but they can add information when the picture is unclear.

The panel is a supportive tool, not a diagnosis. Antibody patterns can be suggestive in some people and absent in others, and inflammatory markers can be elevated for many reasons. A qualified healthcare provider interprets the results together with the full clinical picture and may recommend additional procedures.

  • Perinuclear antineutrophil cytoplasmic antibodies (pANCA)
  • Anti-Saccharomyces cerevisiae antibodies (ASCA IgG and IgA)
  • C-reactive protein (CRP)
  • Erythrocyte sedimentation rate (ESR)
  • Complete blood count with hemoglobin
  • Fecal calprotectin when included
  • Anti-OmpC and anti-CBir1 antibodies when included
  • Serum albumin

Why people order this test

  • Support evaluation of chronic diarrhea or abdominal pain
  • Add laboratory context to a suspected inflammatory bowel condition
  • Distinguish patterns associated with ulcerative colitis and Crohn disease
  • Monitor inflammation in a known digestive condition
  • Investigate blood in the stool with a provider
  • Follow up on abnormal inflammatory markers
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How to prepare

No fasting is required for the blood tests in this order. A sample is collected from a vein, usually at the arm. If a stool test is included, follow the collection instructions provided by the laboratory.

Understanding your results

Results are typically available within one to three business days. The report lists each antibody and inflammatory marker with its value. Findings can support a diagnosis but do not confirm it, so a qualified healthcare provider interprets them with symptoms, imaging, and endoscopy.

Ulcerative Colitis Panel by state

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Frequently Asked Questions

Can this test diagnose ulcerative colitis?

No. It provides supporting laboratory information. Ulcerative colitis is diagnosed through a combination of symptoms, examination, imaging, and endoscopy with biopsy.

What is pANCA?

pANCA stands for perinuclear antineutrophil cytoplasmic antibodies. It is one antibody pattern that clinicians may consider during an inflammatory bowel disease evaluation.

What is ASCA?

ASCA stands for anti-Saccharomyces cerevisiae antibodies. It is another antibody marker used alongside others when evaluating inflammatory bowel disease.

Do I need to fast for this test?

Fasting is not usually required for the blood components. If a stool test is part of the order, follow the specific collection instructions.

Does a negative result rule out ulcerative colitis?

No. Antibody and inflammatory markers are not positive in every person with the condition, so a negative result does not rule it out.

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Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.