Test library
Glutathione Blood Test
The Total Glutathione test measures the body's main antioxidant by combining its reduced and oxidized forms in a blood sample. It is used in wellness and research settings to assess oxidative stress.
Order Total Glutathione Test
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Total Glutathione Test- Typical turnaround
- 1-3 business days
- Starting price
- From $145
- Results
- Confidential, online
Quick answer
The Total Glutathione test measures glutathione, a key antioxidant found in nearly every cell. Total glutathione combines the reduced form, which neutralizes free radicals, and the oxidized form, which is produced during that process. The test is usually ordered in wellness, nutrition, and research contexts to look at oxidative stress, and results are interpreted by a healthcare provider alongside the broader clinical picture.
What this test measures
Glutathione is a small molecule made from three amino acids and is present in high concentrations inside cells. It helps protect tissues from oxidative damage and supports normal immune and detoxification processes. The balance between reduced and oxidized glutathione can shift when the body faces prolonged stress, illness, or poor nutrition, which is why measuring it can be informative.
Total glutathione is most often measured in whole blood or red blood cells, because those samples better reflect long-term intracellular levels than plasma alone. The laboratory may report total glutathione along with the ratio of reduced to oxidized forms. Collection typically involves a blood draw, and special handling may be needed to keep the sample stable.
This test is not a routine diagnostic tool and does not diagnose a specific disease on its own. Levels can be influenced by diet, supplements, exercise, smoking, and general health. A qualified healthcare provider interprets the result within the person's overall health assessment and can discuss whether any follow-up is appropriate.
- Total glutathione (reduced plus oxidized)
- Reduced glutathione (GSH)
- Oxidized glutathione (GSSG)
- GSH to GSSG ratio
- Red blood cell glutathione
- Plasma glutathione
- Cysteine and related amino acids
Why people order this test
- Assess antioxidant status in a wellness or nutrition review
- Support research into oxidative stress
- Follow trends in people with chronic health concerns
- Provide context before discussing diet or lifestyle changes
- Complement other markers of oxidative balance
- Investigate possible nutrient or amino acid insufficiency
How to prepare
No fasting is usually required, but the laboratory may ask for a morning collection or specific handling to protect the sample. Follow the instructions provided with the order, and tell the provider about any supplements you take.
Understanding your results
Results are generally available within one to three business days. The report shows total glutathione and may include the reduced form, the oxidized form, and their ratio. A qualified healthcare provider interprets the values with your history, diet, and other laboratory findings.
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Frequently Asked Questions
What is glutathione?
It is a molecule made from three amino acids and is one of the body's main antioxidants. It helps protect cells from oxidative damage.
What does the total glutathione test measure?
It measures the combined amount of reduced and oxidized glutathione in the sample, which reflects antioxidant status.
Why is the GSH to GSSG ratio reported?
The ratio compares the active reduced form with the oxidized form and can indicate how much oxidative stress the body is under.
Do supplements affect the result?
Yes. Glutathione and related supplements can influence levels, so share a current supplement list with the ordering provider.
Do I need to fast?
Fasting is usually not required, but follow any preparation instructions the laboratory provides.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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