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Insect Venom Allergy Panel

The Stinging Insects Allergy Test measures IgE antibodies to five venomous insects, including honeybee, paper wasp, yellow jacket, and hornet venoms. It helps evaluate sensitivity after a sting reaction.

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Typical turnaround
1-3 business days
Starting price
From $159
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Quick answer

The Stinging Insects Allergy Test is a blood panel that measures immunoglobulin E antibodies against venom from five common stinging insects. It is typically ordered after a significant sting reaction or when a provider wants to assess sensitivity before an exposure. The panel covers honeybee, paper wasp, yellow jacket, yellow hornet, and white-faced hornet venoms, and a qualified healthcare provider interprets the results.

What this test measures

Stinging insects inject venom when they sting, and for some people the immune system produces IgE antibodies against proteins in that venom. A subsequent sting can then trigger an allergic reaction, which may range from local swelling to a body-wide response. Identifying which venoms are involved helps a clinician assess risk and discuss management.

The test uses a blood sample to measure allergen-specific IgE for five venoms: honeybee, paper wasp, yellow jacket, yellow hornet, and white-faced hornet. Each venom is reported separately with a level and a reactivity class. Because some insect venoms share proteins, cross-reactivity is possible, and the pattern of results can help clarify which insects are most relevant.

A positive result shows sensitization to a venom, not the severity of a future reaction. Some people with positive tests never react strongly again, while others do. A qualified healthcare provider uses the result with the sting history, symptoms, and other findings to guide the discussion, and anyone with a history of a severe reaction should seek medical guidance.

  • Honeybee venom-specific IgE
  • Paper wasp venom-specific IgE
  • Yellow jacket venom-specific IgE
  • Yellow hornet venom-specific IgE
  • White-faced hornet venom-specific IgE
  • Total serum IgE
  • IgE reactivity class for each venom

Why people order this test

  • Evaluate sensitivity after a significant sting reaction
  • Identify which insect venoms the immune system recognizes
  • Assess cross-reactivity among related stinging insects
  • Provide objective information before a provider discussion
  • Support planning for people with outdoor or occupational exposure
  • Clarify sensitivity when a broader allergy panel is ordered
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How to prepare

No fasting is required for this blood test. A sample is collected from a vein, usually at the arm. Follow any specific instructions from the laboratory, particularly if the test is part of a larger allergy panel.

Understanding your results

Results are typically available within one to three business days. The report shows the specific IgE level and reactivity class for each venom tested. An elevated result indicates sensitization, and a qualified healthcare provider can explain what it means for a particular person.

Insect Venom Allergy Panel by state

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Frequently Asked Questions

Which insects does this panel test?

It measures IgE antibodies to five venoms: honeybee, paper wasp, yellow jacket, yellow hornet, and white-faced hornet.

When is this test usually ordered?

It is often ordered after a notable sting reaction, or when a provider wants to assess sensitivity in someone with a history of insect allergy.

Does a positive result predict how severe a future reaction will be?

No. A positive result shows sensitization, but it does not predict the severity of a future sting reaction. A healthcare provider interprets it with the sting history.

Can different insect venoms cross-react?

Yes. Some venoms share proteins, so cross-reactivity is possible. The pattern of results across the five venoms helps clarify which insects are most relevant.

Should I fast before this test?

Fasting is not required unless the test is combined with another panel that requires it.

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Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.