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Rat Serum Sensitization Panel

This blood test measures IgE antibodies against rat serum proteins, including albumin found in rat blood. It helps assess sensitization in laboratory staff and others exposed to rats.

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Typical turnaround
1-3 business days
Starting price
From $49
Results
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Quick answer

The Rat Serum Protein Allergy Test is a blood test for IgE antibodies directed at proteins in rat serum, the liquid portion of rat blood. It is used mainly for people who handle rats or their tissues in research, veterinary, or breeding settings. The result indicates whether sensitization to these proteins is present and is interpreted with the person's exposure and symptoms.

What this test measures

Serum contains many proteins, including albumin, that can act as allergens when inhaled or contacted. Rat serum albumin is a well-known animal allergen, and sensitization to it has been reported among laboratory animal workers. Measuring IgE against rat serum proteins helps identify whether this specific fraction of rat material is contributing to symptoms.

The assay uses a single blood sample that is mixed with rat serum proteins to detect antibody binding. Results are reported as a quantitative level in kilounits per liter, often with a graded class. Because exposure to animal serum can happen during procedures, cage cleaning, or handling, the test is often ordered with related rodent and epithelium allergens.

Researchers, animal care staff, and students who work with rats may be offered this test when they report new nasal, eye, or chest symptoms. It can also be used to follow changes in sensitization over time in occupational health programs. A qualified healthcare provider should interpret the result with the work history and clinical picture.

  • Rat serum protein-specific IgE antibodies
  • Rat serum albumin-specific IgE
  • Quantitative IgE to rat serum in kU/L
  • Allergen-specific IgE antibody class
  • Total serum IgE when included
  • Rat epithelium-specific IgE when included in a panel
  • Common rodent allergens when a broader panel is ordered

Why people order this test

  • Assess allergy symptoms in people who handle rat blood or tissue
  • Support occupational health monitoring for laboratory workers
  • Separate serum protein sensitization from epithelium sensitization
  • Add detail to a rodent allergy panel ordered for persistent symptoms
  • Document sensitization when exposure cannot easily be reduced
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How to prepare

No fasting is needed for this blood test. The sample can be collected at any time, and the person should follow the lab's routine instructions for blood draws.

Understanding your results

Results generally return within one to three business days. A measurable IgE level indicates sensitization to rat serum proteins, which may or may not be accompanied by clinical symptoms. The finding is interpreted together with exposure history and other allergy tests.

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Frequently Asked Questions

What are rat serum proteins?

Serum is the clear liquid part of blood after cells are removed. It contains proteins such as albumin that can act as allergens for sensitized individuals.

How is this different from a rat epithelium test?

The epithelium test targets skin and tissue proteins, while this test targets blood proteins. Some people react to one fraction more than the other, and panels often include both.

Who typically orders this test?

It is most often used in occupational health settings for laboratory animal workers, researchers, and others with regular rat contact.

Can this test predict the severity of a reaction?

No. Antibody levels indicate sensitization and do not reliably predict how severe any future reaction might be.

Do I need to stop any medication before testing?

Antibody blood tests are generally unaffected by common medications, but the ordering clinician should be consulted about anything the person takes.

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Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.