Test library
PT PTT Coagulation Blood Test
This panel measures prothrombin time with INR and activated partial thromboplastin time. Together they evaluate different parts of the clotting process.
Order Prothrombin Time (PT) with INR & PTT
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Prothrombin Time (PT) with INR & PTT- Typical turnaround
- 1-3 business days
- Starting price
- From $49
- Results
- Confidential, online
Quick answer
The PT with INR and PTT Panel measures two complementary clotting tests from a single blood sample. Prothrombin time with INR reflects the extrinsic and common clotting pathways, while activated partial thromboplastin time, also called PTT or aPTT, reflects the intrinsic and common pathways. Ordering them together gives a broader view of how the clotting system is functioning and is useful when bleeding or clotting concerns are being evaluated.
What this test measures
The clotting cascade involves a series of proteins that activate one another to form a stable clot. Prothrombin time and aPTT test different entry points into that cascade, so an abnormality in one test can point toward different clotting factors than an abnormality in the other. The INR standardizes the prothrombin time result so it can be compared across laboratories.
The panel requires a blood sample, and results are reported as prothrombin time in seconds, an INR, and the aPTT in seconds. Additional markers such as fibrinogen or thrombin time may be included in an expanded coagulation panel. Reference ranges depend on the laboratory and on the reason the tests were ordered.
People may order this panel when a healthcare provider is investigating unusual bleeding or bruising, evaluating a possible clotting disorder, monitoring certain therapies, or assessing clotting before a procedure. It can also be used in liver-related evaluations. A qualified healthcare provider should interpret the results and decide whether further testing is needed.
- Prothrombin time (PT) in seconds
- International normalized ratio (INR)
- Activated partial thromboplastin time (aPTT or PTT)
- Fibrinogen level when included in an expanded panel
- Thrombin time when included in an expanded panel
- Clotting factor assays when ordered as follow-up testing
Why people order this test
- Evaluate unusual bleeding or bruising
- Investigate a possible inherited or acquired clotting disorder
- Assess clotting function before a procedure when requested
- Monitor anticoagulant therapy as directed by a healthcare provider
- Add detail to a liver or coagulation evaluation
- Compare intrinsic and extrinsic clotting pathway function
How to prepare
No fasting is usually required. A blood sample is collected at the lab, and normal meals are generally acceptable. Inform your healthcare provider and the laboratory about medications, especially those that affect clotting.
Understanding your results
Results are usually available within one to three business days. Each value is interpreted against its reference range and in the context of the clinical question. A qualified healthcare provider should review the results and determine whether additional testing is needed.
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Frequently Asked Questions
What is the difference between PT and PTT?
Prothrombin time assesses the extrinsic and common clotting pathways, while activated partial thromboplastin time assesses the intrinsic and common pathways. Testing both gives a broader picture.
Why order these tests together?
Together they help localize where a clotting problem may lie and provide complementary information that a single test cannot give.
Can this panel diagnose a bleeding disorder?
It provides information that a healthcare provider uses during evaluation. Diagnosing a specific bleeding or clotting disorder may require additional factor testing and clinical assessment.
Do I need to stop my medications before this test?
Do not change or stop any medication on your own. Tell your healthcare provider about your medications so results can be interpreted appropriately.
How is the sample collected?
A blood sample is drawn from a vein, usually in the arm, during a short lab visit.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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