Nationwide collection sitesOrder without a doctor's referralConfidential results

Test library

Norpropoxyphene Urine Test

This urine test screens for propoxyphene, an opioid pain reliever withdrawn from many markets, and can confirm presumptive positive results with a specific method.

Order Propoxyphene Urine Test

Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.

Order Propoxyphene Urine Test
Typical turnaround
1-3 business days
Starting price
From $108
Results
Confidential, online

Quick answer

The Propoxyphene Urine Test is a laboratory screen that looks for propoxyphene, an opioid pain reliever that has been withdrawn from the market in many countries because of safety concerns. The test uses an immunoassay to detect the drug or its metabolite, norpropoxyphene, in a urine sample. Presumptive positive results can be confirmed with a more specific method. Results are interpreted in context by the ordering professional.

What this test measures

Propoxyphene was prescribed for pain relief and is related to methadone and other opioids. After use, it is broken down into norpropoxyphene, which can remain detectable in urine for some time. The screening immunoassay compares the sample signal to a laboratory cutoff and reports the result as positive or negative relative to that threshold.

When a screen is presumptive positive, confirmation by liquid chromatography with tandem mass spectrometry or gas chromatography with mass spectrometry can identify propoxyphene or its metabolite and report a concentration. Laboratories may also perform specimen validity testing, including creatinine, pH, and specific gravity, to assess whether the sample is suitable for analysis.

This test may be ordered in clinical or authorized testing settings and should be requested through an appropriate provider or program. Detection depends on the amount used, frequency, hydration, and individual metabolism, so timing cannot be determined precisely from a result. The ordering professional interprets the findings.

  • Propoxyphene urine immunoassay screen
  • Norpropoxyphene metabolite detection
  • Qualitative screen result relative to the laboratory cutoff
  • Confirmatory propoxyphene testing by mass spectrometry when indicated
  • Propoxyphene or norpropoxyphene concentration when confirmation is performed
  • Urine specimen validity checks when included

Why people order this test

  • Screen for propoxyphene exposure in a clinical or authorized setting
  • Confirm a presumptive positive urine screen with a specific method
  • Add laboratory information to an authorized testing process
  • Support a professional evaluation of unexpected symptoms
  • Document findings with a confirmed result when requested
Order lab testing onlineChoose from hundreds of panels, order online, and visit a certified collection site near you.
Order Norpropoxyphene Urine Test

How to prepare

No fasting is required. A urine sample is collected at the lab according to its instructions. Tell the laboratory about medications you take, since some compounds can interfere with immunoassay screening.

Understanding your results

Results are usually available within one to three business days. A negative screen indicates that propoxyphene was not detected at the laboratory cutoff, while a presumptive positive result should be confirmed with a specific method before conclusions are drawn.

Norpropoxyphene Urine Test by state

Related tests

Frequently Asked Questions

Is propoxyphene still prescribed?

It has been withdrawn from the market in many countries because of safety concerns, but its use may still be encountered historically. Testing can detect recent exposure.

What is norpropoxyphene?

Norpropoxyphene is the main metabolite formed when the body breaks down propoxyphene. It can be detected in urine and is targeted by screening and confirmation methods.

Why is confirmation testing important?

Immunoassays can react to substances other than the target drug. Mass spectrometry confirmation identifies propoxyphene or its metabolite specifically, reducing the chance of a false positive.

How long can propoxyphene be detected in urine?

Detection windows vary with dose, frequency of use, hydration, and individual metabolism. A negative result does not necessarily rule out earlier use.

How is the sample collected?

A urine sample is provided at the laboratory following its collection instructions. No blood draw is required for this test.

Ready to get tested?

Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.

Order Norpropoxyphene Urine Test

Reviewed by the LabOrdering Editorial Team

Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.