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Parathyroid Hormone Test

A Parathyroid Hormone test measures PTH, the hormone that regulates blood calcium. It is used to evaluate parathyroid function and is interpreted together with calcium and related tests.

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Typical turnaround
1-3 business days
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From $158
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Quick answer

The Parathyroid Hormone test measures the level of PTH in the blood. PTH is released by the parathyroid glands and is the main regulator of calcium balance in the body. The test is usually interpreted alongside a calcium measurement, because together they help show whether the parathyroid glands are responding appropriately.

What this test measures

The parathyroid glands sit near the thyroid in the neck and release PTH in response to low blood calcium. PTH raises calcium by acting on bone, the kidneys, and the gut. Because calcium and PTH work in a tight feedback loop, measuring PTH alone can be misleading, so clinicians typically review it with calcium and sometimes vitamin D or phosphate.

Testing may be ordered when a routine blood test shows abnormal calcium, or when someone has symptoms that could relate to parathyroid function, such as bone discomfort, kidney stones, or fatigue. It can also be used to follow a known parathyroid condition or to investigate an unclear calcium problem.

Interpretation depends on context. A high PTH with a high calcium points in one direction, while a high PTH with a low calcium points in another. Results can be influenced by vitamin D status, kidney function, and medications, so a qualified healthcare provider evaluates the whole picture before drawing conclusions.

  • Parathyroid hormone (PTH), also called parathormone
  • Serum calcium, often ordered at the same draw
  • Ionized calcium when requested
  • Vitamin D (25-hydroxyvitamin D)
  • Phosphate (phosphorus)
  • Magnesium
  • Albumin, used to adjust total calcium
  • Serum creatinine to assess kidney function

Why people order this test

  • Investigate an abnormal calcium result
  • Evaluate suspected parathyroid overactivity or underactivity
  • Support the workup of kidney stones or bone concerns
  • Monitor a known parathyroid condition over time
  • Check PTH after parathyroid surgery
  • Clarify the cause of unexplained fatigue or bone discomfort
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How to prepare

Fasting may be requested depending on which tests are bundled with the order, since calcium and some related markers are sometimes measured after fasting. A blood sample is collected from a vein. Follow the timing and preparation instructions provided by the laboratory.

Understanding your results

Results are usually available within one to three business days. The report shows the PTH level, which is interpreted together with calcium and any related tests. Values outside the reference range do not diagnose a condition by themselves, so a qualified healthcare provider evaluates them in context.

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Frequently Asked Questions

What does parathyroid hormone do?

PTH regulates calcium in the blood. It raises calcium by acting on bone, the kidneys, and the gut, helping keep levels within a narrow range.

Why is calcium tested with PTH?

The two are interpreted together. The relationship between PTH and calcium helps clinicians understand whether an abnormality involves the parathyroid glands or another cause.

Do I need to fast for this test?

Fasting may be requested depending on which tests are ordered with it. Follow the preparation instructions supplied with the order.

Can vitamin D affect the result?

Yes. Vitamin D status influences calcium and PTH, so it is often measured alongside them to give a fuller picture.

Where are the parathyroid glands?

They are four small glands located near the thyroid gland in the neck. Despite the similar name, they have a different function from the thyroid.

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Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.