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Oxycodone and Metabolites Urine Screen

This urine drug screen detects oxycodone, oxymorphone, and related metabolites. It is used in clinical monitoring, workplace testing, and personal checks to identify recent use of these prescription opioids.

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Typical turnaround
1-3 business days
Starting price
From $118
Results
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Quick answer

The Oxycodone and Oxymorphone screen is a urine drug test that looks for these opioid medications and the metabolites they leave behind. It is used across clinical, workplace, legal, and personal testing settings. Because immunoassay screens can be affected by cross-reactive substances, any presumptive positive is normally confirmed with a more specific method.

What this test measures

Oxycodone is a widely prescribed opioid pain medication, and oxymorphone is a related opioid that also appears as a metabolite of oxycodone. Screening for both, along with their metabolites, improves the chance of detecting recent use. The assay used for this test is designed to be more specific than broad opiate screens, which may not reliably detect synthetic or semisynthetic opioids.

The sample is urine, collected at a laboratory or collection site under standard procedures. An initial immunoassay provides a presumptive result, and a positive finding is typically confirmed with mass spectrometry or a similar technique. Detection windows vary by the amount used, how often it is used, and the person's metabolism.

A screening result is not a diagnosis and does not measure impairment. It reports whether the targeted compounds were present above the laboratory cutoff at the time of collection. A qualified healthcare provider or the requesting organization interprets the result with the appropriate context, and disclosing current prescriptions supports accurate review.

  • Oxycodone
  • Oxymorphone
  • Noroxycodone metabolite
  • Noroxymorphone metabolite
  • Opiate class markers when included
  • Creatinine, used to assess sample validity

Why people order this test

  • Screen for recent use of oxycodone or oxymorphone
  • Monitor adherence to a prescribed pain medication plan
  • Support workplace or pre-employment drug testing
  • Follow up after an unexpected opioid screen result
  • Check for non-prescribed opioid use in a clinical setting
  • Provide documentation as part of a monitoring program
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How to prepare

No fasting is required for a urine drug screen. Follow the collection instructions provided by the laboratory. Let the testing provider know about prescription and over-the-counter medications, since some can affect screening results.

Understanding your results

Results are typically reported within one to three business days. A negative result indicates the targeted drugs were not detected above the cutoff, while a presumptive positive is usually confirmed with a more specific method. A qualified healthcare provider can explain the meaning of the final report.

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Frequently Asked Questions

What does the oxycodone urine screen check for?

It screens for oxycodone, oxymorphone, and their metabolites in a urine sample.

How is the sample collected?

A urine sample is provided at a laboratory or collection site according to the site's standard procedures.

How long do these drugs stay detectable?

Detection windows depend on dose, frequency of use, and individual metabolism. The screen targets recent use rather than older exposure.

Is a positive screen final?

No. Initial immunoassay results are presumptive. A positive screen is normally confirmed with a more specific technique before it is treated as definitive.

Can other medications cause a false positive?

Some medications can cross-react with immunoassays. Sharing a complete medication list helps reviewers interpret unexpected results.

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Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.