Test library
Lettuce Sensitization Test
The Lettuce Allergy Test measures IgE antibodies to lettuce proteins. Lettuce allergy is uncommon, and testing helps assess sensitization when reactions follow eating lettuce or handling the leaves.
Order Lettuce Allergy Test
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Lettuce Allergy Test- Typical turnaround
- 1-3 business days
- Starting price
- From $49
- Results
- Confidential, online
Quick answer
The Lettuce Allergy Test detects IgE antibodies against proteins in lettuce. Lettuce is a leafy vegetable used in salads, sandwiches, and wraps. Allergy to lettuce is uncommon but can cause oral itching, hives, or digestive symptoms, and reactions may also occur after handling the leaves. The test helps determine whether an allergic sensitization to lettuce is present.
What this test measures
Lettuce allergy involves an immune response to proteins in the leaves. Several varieties, including romaine, iceberg, and butterhead, are used in food. Some people with pollen allergy react to lettuce because of cross-reactive proteins, a pattern seen with certain fresh vegetables.
The test measures specific IgE antibodies to lettuce in a blood sample. A detectable level indicates sensitization, which may or may not be accompanied by symptoms. Results are interpreted with the food history and any related pollen sensitizations. A food and symptom diary can add helpful context for the clinician.
Testing may be considered when someone reports itching, tingling, hives, or digestive discomfort after eating lettuce, or skin symptoms after handling it. A qualified healthcare provider should interpret the result and advise on management. Noting whether symptoms follow raw or cooked lettuce can be helpful.
- Lettuce-specific IgE antibodies
- Quantitative sIgE concentration reported in kU/L
- Allergen-specific IgE class on a graded scale
- Total serum IgE when included
- Blood eosinophil count when included
- Related pollen or vegetable markers when a panel is included
Why people order this test
- Assess sensitization after reactions to lettuce
- Help evaluate oral itching, hives, or skin symptoms with exposure
- Add objective information when a vegetable allergy is suspected
- Check for cross-reactivity with pollen
- Support a clinician's allergy management plan
- Provide context when salads or wraps trigger symptoms
How to prepare
No fasting is required for this blood test. Follow the collection instructions provided by the laboratory, and note whether symptoms followed eating, handling, or preparing lettuce.
Understanding your results
Results are usually available within one to three business days. A detectable level indicates sensitization to lettuce, but not everyone who is sensitized develops symptoms. A qualified healthcare provider should interpret the findings with the reaction history.
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Frequently Asked Questions
Is lettuce allergy common?
Lettuce allergy is uncommon compared with allergies to foods such as peanut, milk, or egg. It is still reported and can be evaluated when symptoms occur.
Can lettuce allergy be related to pollen allergy?
Yes. Some people with pollen allergy react to lettuce and other fresh vegetables because of cross-reactive proteins.
Does cooking lettuce change the reaction?
Heating can change some proteins, and reactions may differ between raw and cooked forms. A healthcare provider can assess the specific pattern.
What symptoms should prompt testing?
Oral itching or tingling, hives, swelling, or digestive symptoms after lettuce are common reasons to consider allergy testing.
Does a positive test mean I must avoid all leafy vegetables?
Not necessarily. It shows sensitization to lettuce. A healthcare provider can advise on which foods to avoid or evaluate further.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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