Test library
Herpes 2 Blood Test
The HSV-2 blood test detects type-specific IgG antibodies against herpes simplex virus type 2, the virus most often linked to genital herpes. It can show prior exposure even when no symptoms are present.
Order Genital Herpes (HSV-2) Blood Test
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Genital Herpes (HSV-2) Blood Test- Typical turnaround
- 1-3 business days
- Starting price
- From $45
- Results
- Confidential, online
Quick answer
The Genital Herpes test looks for IgG antibodies against herpes simplex virus type 2 in a blood sample. HSV-2 most often causes genital herpes, though many people who carry it have no noticeable outbreaks. Blood testing can reveal exposure that a visual exam would miss because it detects the immune response rather than the sore itself.
What this test measures
HSV-2 is one of two herpes simplex viruses. It spreads mainly through sexual contact and commonly causes genital infection, though it can also affect other areas. After infection, the virus remains in the body and the immune system keeps producing antibodies, which is what the test measures.
The HerpeSelect assay is type-specific, so it distinguishes HSV-2 from HSV-1. A blood sample is drawn from a vein, and no active lesion is required. Antibodies take time to develop after exposure, so testing too early can produce a negative result even when infection is present.
A positive result indicates prior exposure to HSV-2, not when the infection occurred or how often symptoms will appear. Many carriers have mild or unrecognized symptoms. A healthcare provider interprets the result with the person's history and can discuss monitoring and transmission.
- HSV-2 type-specific IgG antibodies
- HSV-2 index value (HerpeSelect)
- HSV-2 antibody level
- HSV-1 type-specific IgG when ordered together
- HSV-1 and HSV-2 differentiation ratio
- Total HSV IgG when included
Why people order this test
- Check whether a person has been exposed to HSV-2
- Evaluate genital symptoms when the cause is unclear
- Test for herpes when no active lesion is available
- Distinguish HSV-2 from HSV-1 exposure
- Screen as part of a sexual health workup
- Follow up after a possible exposure
How to prepare
No fasting is required. A blood sample is collected from a vein, usually at the arm. Because antibodies take time to develop, ask the laboratory or a provider about the best timing after a possible exposure.
Understanding your results
Results are usually reported within one to three business days. The report gives an index value and a positive or negative interpretation for HSV-2. A healthcare provider can explain what a low-positive or borderline result means.
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Frequently Asked Questions
What does the HSV-2 test detect?
It detects type-specific IgG antibodies against herpes simplex virus type 2, which indicates prior exposure to that virus.
Can HSV-2 be present without symptoms?
Yes. Many people with HSV-2 have mild or no noticeable symptoms, so a blood test can reveal exposure that a visual exam would not.
How soon after exposure should I test?
Antibodies take several weeks to develop. Testing too soon can give a negative result, so a provider may recommend repeat testing at a later point.
Does the test require an active sore?
No. The blood test detects antibodies and works even when there are no active sores or lesions.
Is fasting needed?
No. Fasting is not required for this blood test unless it is combined with other tests that require it.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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