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HSV-1 and HSV-2 Antibody Test

Type-specific herpes testing uses the HerpeSelect method to detect IgG antibodies against HSV-1 and HSV-2 separately. It helps show which herpes virus a person has been exposed to, even without symptoms.

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Typical turnaround
1-3 business days
Starting price
From $158
Results
Confidential, online

Quick answer

This type-specific herpes blood test uses the HerpeSelect method to look for IgG antibodies against herpes simplex virus type 1 and type 2. Distinguishing the two types matters because they tend to cause different patterns of infection, though both can affect oral and genital areas. The test uses a blood sample and can detect exposure even when no symptoms have appeared.

What this test measures

Herpes simplex virus exists as two closely related types. HSV-1 is commonly linked to oral cold sores, while HSV-2 is commonly linked to genital herpes, but either type can infect either site. Type-specific antibody tests distinguish the two, which is more informative than older tests that reported herpes without specifying the type.

The HerpeSelect assay detects IgG antibodies that the immune system produces after infection. Antibodies take time to develop, so testing too soon after exposure can give a negative result. The test requires a blood sample and does not need a lesion swab, which is helpful when someone has no active sores.

A positive result indicates prior exposure to that virus type; it does not show when infection occurred or how often symptoms will appear. Many people with HSV carry it without noticeable outbreaks. A qualified healthcare provider interprets results with the person's history and can discuss transmission and management.

  • HSV-1 type-specific IgG antibodies
  • HSV-2 type-specific IgG antibodies
  • HerpeSelect HSV-1 index value
  • HerpeSelect HSV-2 index value
  • HSV-1 and HSV-2 differentiation ratio
  • Total HSV IgG when included

Why people order this test

  • Distinguish HSV-1 from HSV-2 exposure
  • Check for herpes after a possible exposure
  • Evaluate herpes when no active sores are present
  • Confirm a clinical suspicion before discussing management
  • Screen as part of a broader sexual health workup
  • Provide clarity for a partner discussion with a provider
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How to prepare

No fasting is required. A blood sample is drawn from a vein, usually at the arm. Because antibodies take time to appear, the laboratory may advise on appropriate timing after a possible exposure.

Understanding your results

Results are usually available within one to three business days. The report shows index values and positive or negative results for HSV-1 and HSV-2 separately. A healthcare provider interprets borderline or low-positive values with the person's history.

HSV-1 and HSV-2 Antibody Test by state

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Frequently Asked Questions

What is type-specific herpes testing?

It is a blood test that detects antibodies against HSV-1 and HSV-2 separately, rather than reporting herpes as a single result.

Can the test detect herpes if I have no symptoms?

Yes. The test measures the immune response, so it can detect prior exposure even when no sores or other symptoms are present.

How soon after exposure can I test?

Antibodies take time to develop, so testing too early can produce a false negative. A healthcare provider can advise on the best timing for a repeat test.

What does a low-positive result mean?

Low-positive index values can be less certain than clearly positive results. Providers sometimes recommend repeat testing or an additional method to confirm.

Do I need to fast?

No fasting is needed for this blood test unless it is combined with other tests that require it.

Ready to get tested?

Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.

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Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.