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Hepatitis Blood Test

Hepatitis testing uses blood samples to look for hepatitis A, B, and C infection and related liver markers. It is ordered for symptoms, possible exposure, or routine screening.

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Typical turnaround
1-3 business days
Starting price
From $239
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Quick answer

Hepatitis testing refers to a group of blood tests that look for hepatitis A, B, and C infection and for signs of liver inflammation. Depending on the order, it may include viral antigens, antibodies, or liver enzyme levels. Testing is used when someone has symptoms, has had a possible exposure, or is being screened as part of routine care. A healthcare provider interprets the results.

What this test measures

Hepatitis is inflammation of the liver, and viral hepatitis A, B, and C are among the most common causes. The viruses spread in different ways and leave different markers in the blood. A hepatitis workup selects the tests that fit the question, whether that is active infection, past exposure, or liver inflammation. Results are read together rather than in isolation.

Blood is the sample for hepatitis testing. Serologic tests detect antibodies and antigens, such as hepatitis B surface antigen or hepatitis C antibody, while molecular tests detect viral genetic material like HCV RNA. Liver enzymes including ALT and AST can show that the liver is under stress but do not identify which virus is responsible.

Testing may be ordered after symptoms such as fatigue, jaundice, dark urine, or abdominal discomfort, or after a possible exposure. It is also part of routine screening for some groups and of monitoring during treatment. A qualified healthcare provider interprets results and decides whether further testing or follow-up is needed.

  • Hepatitis A IgM antibody
  • Hepatitis A total antibody
  • Hepatitis B surface antigen (HBsAg)
  • Hepatitis B surface antibody (anti-HBs)
  • Hepatitis B core antibody (anti-HBc)
  • Hepatitis B core IgM antibody
  • Hepatitis B e antigen (HBeAg)
  • Hepatitis C antibody (anti-HCV)
  • Hepatitis C RNA (HCV RNA)
  • Alanine aminotransferase (ALT)
  • Aspartate aminotransferase (AST)
  • Total bilirubin

Why people order this test

  • Investigate symptoms such as jaundice, fatigue, or abdominal discomfort
  • Follow up after a possible exposure to hepatitis
  • Screen as part of routine or prenatal care
  • Monitor a known hepatitis infection over time
  • Check liver enzyme levels alongside viral markers
  • Evaluate risk before starting certain treatments
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How to prepare

Some hepatitis tests do not require preparation, while others may ask for fasting if liver enzymes or a lipid panel are included. Follow the instructions provided with the order and inform the laboratory of current medications.

Understanding your results

Results are usually reported within one to three business days. The report lists each marker as reactive or non-reactive, positive or negative, along with any numeric levels. A healthcare provider explains what the pattern means.

Hepatitis Blood Test by state

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Frequently Asked Questions

What does hepatitis testing check for?

It checks for markers of hepatitis A, B, and C infection, such as viral antigens and antibodies, and sometimes liver enzymes that show inflammation.

Can hepatitis be present without symptoms?

Yes. Many people with hepatitis, especially chronic hepatitis B or C, have no obvious symptoms. That is one reason screening is recommended for certain groups.

Is a blood sample the only sample used?

Hepatitis testing uses a blood sample. The specific tubes and tests depend on which viruses and markers are included in the order.

What is the difference between antibody and RNA tests?

Antibody tests show the immune response to the virus, while RNA tests detect the virus's genetic material directly. They provide different information and are sometimes used together.

Do I need to fast before hepatitis testing?

Fasting is not usually needed for viral markers, but it may be requested if liver enzymes or a lipid panel are part of the same order.

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Reviewed by the LabOrdering Editorial Team

Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.