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Estrone Blood Test

An estrone test measures estrone, a form of estrogen that becomes the main circulating estrogen after menopause. It is used in detailed hormone evaluations.

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Typical turnaround
1-3 business days
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From $198
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Quick answer

An estrone test measures the level of estrone, one of the three main estrogens in the body. Estrone is produced in the ovaries, adrenal glands, and fat tissue, and it becomes the dominant circulating estrogen after menopause. It is usually ordered as part of a broader hormone evaluation, and results are interpreted by a qualified healthcare provider.

What this test measures

Estrone is one of a group of hormones called estrogens, along with estradiol and estriol. During the reproductive years, estradiol is the most abundant, while estrone becomes the main circulating estrogen after menopause. Estrone can be produced from androgens in fat tissue, so body composition can influence its level.

The test uses a serum sample collected from a vein and reports a quantitative estrone level. It is often ordered together with estradiol, total estrogens, or reproductive hormones such as follicle-stimulating hormone and luteinizing hormone. Timing can matter for menstruating women because estrogen levels shift through the cycle.

People may order this test when a provider wants more detail about estrogen status than a single estradiol measurement provides, such as during menopause-related evaluation or hormone therapy monitoring. Because estrone is one part of a larger picture, a qualified healthcare provider should interpret the result with your symptoms, history, and related hormone tests.

  • Estrone
  • Estradiol
  • Total estrogens (when included)
  • Follicle-stimulating hormone (FSH)
  • Luteinizing hormone (LH)
  • Sex hormone-binding globulin (when included)
  • Progesterone (when included)

Why people order this test

  • Detailed estrogen evaluation
  • Menopause-related hormone review
  • Monitor hormone therapy with a provider
  • Assess estrogen balance alongside estradiol
  • Part of a broader hormone panel
  • Establish a baseline before a provider visit
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How to prepare

Timing may matter for menstruating women, so a provider may specify the cycle day for collection. Fasting is not usually required. A blood sample is collected from a vein. Follow the instructions provided with your order.

Understanding your results

Results are generally available within 1-3 business days. Reference ranges vary by sex, age, and cycle timing, and estrone is interpreted alongside other estrogen measurements. A qualified healthcare provider should explain what the value suggests in the context of your health.

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Frequently Asked Questions

What is estrone?

Estrone is one of the main estrogens. It becomes the dominant circulating estrogen after menopause and can be produced from androgens in fat tissue.

How is estrone different from estradiol?

Both are estrogens. Estradiol is more potent and dominates during the reproductive years, while estrone is the main circulating estrogen after menopause.

Why measure estrone rather than only estradiol?

Estrone can provide additional detail about overall estrogen status, particularly after menopause or during hormone therapy monitoring.

Do I need to fast?

Fasting is not usually required unless other components of the panel call for it.

Can one result diagnose a condition?

No. It is one measurement that a qualified healthcare provider interprets with symptoms, history, and other tests.

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Reviewed by the LabOrdering Editorial Team

Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.

Medical disclaimer. The information on LabOrdering.com is educational only and is not medical advice, diagnosis, or treatment. Reference ranges and clinical guidance vary between laboratories. Always consult a qualified healthcare provider about your own results and care.