Test library
Citrus Fruit IgE Panel
This citrus allergy panel measures IgE antibodies to orange, lime, lemon, tangerine, and grapefruit, helping identify which citrus fruits may be involved in allergic symptoms after contact or consumption.
Order Citrus Fruit Allergy Test Panel
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Citrus Fruit Allergy Test Panel- Typical turnaround
- 1-3 business days
- Starting price
- From $159
- Results
- Confidential, online
Quick answer
The citrus fruit allergy panel is a blood test that checks immunoglobulin E responses to five common citrus fruits: orange, lime, lemon, tangerine, and grapefruit. It suits people who notice oral itching, skin reactions, or digestive symptoms after eating or handling citrus. Results are reviewed by a healthcare provider alongside your exposure history.
What this test measures
This panel measures allergen-specific immunoglobulin E antibodies against five citrus fruits in a single blood sample. Each fruit is reported separately, so the result can show whether one citrus variety stands out or whether several share reactivity. Immunoassays quantify antibodies in kilounits per liter and assign a class from zero to six. Clinicians use the panel when citrus allergy is suspected but the specific trigger is unclear.
The sample is collected by venipuncture at a partner laboratory. The laboratory prepares extracts from orange, lime, lemon, tangerine, and grapefruit and measures antibody binding to each. Supporting markers such as total IgE and eosinophil counts may be reported alongside the fruit-specific results. Cross-reactivity with pollen proteins is also possible because some citrus proteins resemble those found in certain pollens.
People order this panel after reacting to citrus fruit, juice, peel, or zest. Reactions can include oral itching, lip swelling, hives, or gastrointestinal discomfort, and they may occur with raw fruit more often than with cooked or processed forms. The panel provides objective information for an allergy discussion, though it does not replace a clinical evaluation and cannot predict reaction severity.
- Orange-specific IgE antibodies
- Lime-specific IgE antibodies
- Lemon-specific IgE antibodies
- Tangerine-specific IgE antibodies
- Grapefruit-specific IgE antibodies
- Total serum IgE
- Blood eosinophil count
Why people order this test
- Identify which citrus fruit may be triggering symptoms
- Evaluate oral itching or swelling after eating citrus
- Assess suspected cross-reactivity among citrus varieties
- Gather objective data before an elimination trial
- Support allergy planning for children or adults
How to prepare
No fasting is typically needed for this allergy panel, and one blood draw is sufficient. Follow the laboratory instructions you receive, and let the collector know about any medications or recent reactions.
Understanding your results
Results are usually ready within one to three business days. Individual fruit results show which citrus-specific IgE antibodies are present, but sensitization does not always mean a clinical allergy. A healthcare provider interprets the panel with your symptoms and history.
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Frequently Asked Questions
Does the citrus panel include all citrus fruits?
It covers five common varieties: orange, lime, lemon, tangerine, and grapefruit. Other citrus fruits are not part of this specific panel.
Can I react to citrus peel but not the fruit?
Yes. Some people react to proteins or oils in the peel or zest. Testing can help clarify sensitization, while a provider evaluates the pattern of exposure.
Is fasting required?
No fasting is typically required. Follow any instructions provided by the laboratory.
What does a positive citrus result mean?
It means IgE antibodies to that fruit were detected. Only a healthcare provider can determine whether those antibodies explain your symptoms.
Can citrus allergy be outgrown?
Some food allergies change over time, and citrus allergy behavior varies by person. A provider can reassess if symptoms change or disappear.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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Every page on this site is reviewed for clarity, sourcing, and accuracy. We update our library as testing options, collection networks, and accreditation standards change.