Test library
CBC with Diff Test
The Complete Blood Count with Differential measures red blood cells, white blood cells, platelets, hemoglobin, and the five white cell types. It is a broad test used to screen for anemia, infection, inflammation, and blood disorders.
Order Complete Blood Count Test (CBC Test) with Differential
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Complete Blood Count Test (CBC Test) with Differential- Typical turnaround
- 1-3 business days
- Starting price
- From $28
- Results
- Confidential, online
Quick answer
The Complete Blood Count with Differential is a common blood test that gives an overall picture of the blood. It measures red blood cells, white blood cells, and platelets, and the differential breaks the white cells into five types. It is used to screen for anemia, infection, inflammation, and disorders of the bone marrow. A qualified healthcare provider interprets the results with the clinical picture.
What this test measures
A complete blood count is one of the most frequently ordered laboratory tests. The main portion measures hemoglobin, hematocrit, red blood cell count, and red cell indices such as MCV and MCH, which describe cell size and hemoglobin content. These values help detect and classify anemia, and platelets, which are involved in clotting, are also counted.
The differential adds detail about the white blood cells, reporting the percentage and absolute numbers of neutrophils, lymphocytes, monocytes, eosinophils, and basophils. This breakdown can suggest whether an infection is bacterial or viral, whether an allergic or parasitic process is present, or whether a bone marrow problem should be considered. The sample is a routine blood draw.
Clinicians order a CBC with differential for a wide range of reasons, from routine checkups to investigating fatigue, fever, bruising, or an abnormal result on another test. It is also used to monitor known conditions and the effects of some treatments. Results are interpreted with symptoms and other testing rather than on their own.
- Hemoglobin
- Hematocrit
- Red blood cell count
- MCV, MCH, and MCHC
- RDW
- White blood cell count
- Neutrophils
- Lymphocytes
- Monocytes
- Eosinophils
- Basophils
- Platelet count
Why people order this test
- Screen for anemia or low blood counts
- Investigate fever, infection, or inflammation
- Evaluate fatigue, weakness, or bruising
- Monitor a known blood or bone marrow condition
- Check the effect of certain treatments
- Follow up on an abnormal result from another test
How to prepare
No fasting is usually required for a complete blood count with differential. A blood sample is drawn from a vein, typically at the arm. Follow any specific instructions provided with the order, especially if other tests are included.
Understanding your results
Results are usually reported within one to three business days. The report lists each cell count and index with a reference range. Values outside the range can point to anemia, infection, inflammation, or other conditions, and a qualified healthcare provider interprets them in context.
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Frequently Asked Questions
What does a CBC with differential measure?
It measures red blood cells, hemoglobin, hematocrit, red cell indices, white blood cells, the five white cell types, and platelets.
Why is a differential included?
The differential shows the proportion and absolute numbers of each white cell type, which can help distinguish infection, allergy, and other processes.
Do I need to fast for a CBC?
Fasting is not usually required for a complete blood count, though other tests ordered at the same time may require it.
What can an abnormal result mean?
Abnormal counts can be linked to anemia, infection, inflammation, bleeding, or bone marrow conditions. A provider reviews the result with the full clinical picture.
How is the sample collected?
A routine blood draw from a vein, usually at the arm.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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