Test library
Autoimmune Blood Test Panel
The Autoimmune Disorder Panel screens for several autoantibodies and inflammation markers linked to autoimmune conditions. It combines tests such as ANA, rheumatoid factor, and inflammatory markers to support a broader evaluation.
Order Autoimmune Disorder Panel
Order online and visit a local collection site, or choose an at-home kit where available. No referral and no insurance required.
Order Autoimmune Disorder Panel- Typical turnaround
- 1-3 business days
- Starting price
- From $198
- Results
- Confidential, online
Quick answer
The Autoimmune Disorder Panel groups several blood tests that look for autoantibodies and inflammation markers. Autoantibodies are proteins the immune system makes against the body's own tissues, and they can appear in conditions such as lupus, rheumatoid arthritis, and related disorders. The panel supports a broader evaluation and is interpreted alongside symptoms and examination findings.
What this test measures
Autoimmune conditions develop when the immune system mistakenly targets healthy tissue. Because different conditions target different tissues, no single test covers everything. A panel approach checks several markers at once, which helps clinicians decide whether more focused testing is warranted based on the pattern of results.
The panel typically includes antinuclear antibodies, rheumatoid factor, anti-CCP, inflammatory markers such as ESR and CRP, and sometimes complement proteins. Each marker reflects a different part of the immune response. Some markers are sensitive but not specific, meaning they can be abnormal in people who do not have an autoimmune disease.
Results are reviewed as a group rather than in isolation. A positive marker does not by itself confirm a diagnosis, and a negative panel does not rule one out. Clinicians combine the findings with symptoms, physical examination, and sometimes imaging or referral to a specialist.
- Antinuclear antibodies (ANA)
- Anti-double-stranded DNA (anti-dsDNA)
- Rheumatoid factor (RF)
- Anti-cyclic citrullinated peptide (anti-CCP)
- Erythrocyte sedimentation rate (ESR)
- C-reactive protein (CRP)
- Complement C3 and C4
- Anti-SSA (Ro) and anti-SSB (La) antibodies
Why people order this test
- Investigate persistent joint pain, rash, or unexplained fatigue
- Support the workup of a suspected autoimmune condition
- Follow up on an abnormal ANA or inflammatory marker
- Distinguish between different patterns of autoantibody reactivity
- Monitor known autoimmune activity over time
- Provide objective information before a specialist referral
How to prepare
No fasting is usually required for this panel. A blood sample is drawn from a vein, typically at the arm. Follow any instructions from the laboratory, and share a current medication list with the ordering provider since some treatments can affect results.
Understanding your results
Results are generally available within one to three business days. Each marker is reported separately with its own reference range. Patterns across the panel are more meaningful than any single value, and a qualified healthcare provider interprets the results with the person's symptoms.
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Frequently Asked Questions
What does the autoimmune panel test for?
It checks several autoantibodies and inflammation markers, such as ANA, rheumatoid factor, anti-CCP, ESR, and CRP, to support evaluation of autoimmune conditions.
Does a positive result mean I have an autoimmune disease?
No. A positive marker shows immune activity that may be relevant, but it does not confirm a diagnosis on its own. Results are interpreted with symptoms and examination.
Do I need to fast for this panel?
Fasting is not usually required. If the order is combined with tests that need fasting, the laboratory provides the instructions.
Can the panel be normal even if I have symptoms?
Yes. Some autoimmune conditions do not show abnormal markers on a broad panel, so a normal result does not rule out a diagnosis.
Why are several tests grouped together?
Different conditions produce different markers. Grouping them gives a wider view and helps guide which focused tests, if any, should follow.
Ready to get tested?
Order online and visit a collection site near you, or choose a mail-in kit. No referral and no insurance required.
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